Shalom Michaeli

Dr. Michaeli is Associate Professor in the Department of Radiology at Center for Magnetic Resonance Research (CMRR) at the University of Minnesota. He received his PhD in Physical Chemistry in 1996 from the Hebrew University of Jerusalem, Israel. His research is focused on relaxations during radiofrequency irradiation and development of non-invasive contrast methods for Magnetic Resonance (MR) imaging and spectroscopy at high magnetic fields (3T and higher). This research effort has resulted in numerous contributions that have fundamentally impacted brain and body research. Rotating frame relaxation methods based on adiabatic pulses were first developed at the CMRR. Dr. Michaeli’s lab followed this development with a large body of work (utilizing theoretical modeling and experiments) investigating different relaxation pathways in vivo at different magnetic field strengths. The novel adiabatic T1ρ and T2ρ methods were proven to provide an excellent tool for investigation of neurodegenerative processes in Parkinson’s disease, Multiple Sclerosis as well as cancer and stroke. Recently Dr. Michaeli’s group has developed another rotating frame method that comprises two relaxation pathways, T1ρ and T2ρ. This method provides greater sensitivity to molecular motion and is entitled Relaxation Along a Fictitious Field (RAFF). Utilization of these novel MRI contrasts is the foundation of the MICROABRADAM project. Dr. Michaeli co-authored more than 50 publications in peer-reviewed journals, is co-inventor on four patents, is funded by several intramural and extramural grants, and serves as a reviewer for a variety of scientific journals.